scvelo.pp.pca¶

scvelo.pp.
pca
(data, n_comps=None, zero_center=True, svd_solver='arpack', random_state=0, return_info=False, use_highly_variable=None, dtype='float32', copy=False, chunked=False, chunk_size=None)¶ Principal component analysis [Pedregosa11].
Computes PCA coordinates, loadings and variance decomposition. Uses the implementation of scikitlearn [Pedregosa11].
Changed in version 1.5.0: In previous versions, computing a PCA on a sparse matrix would make a dense copy of the array for mean centering. As of scanpy 1.5.0, mean centering is implicit. While results are extremely similar, they are not exactly the same. If you would like to reproduce the old results, pass a dense array.
Parameters:  data :
AnnData
,ndarray
,spmatrix
The (annotated) data matrix of shape n_obs × n_vars. Rows correspond to cells and columns to genes.
 n_comps :
int
,None
Number of principal components to compute. Defaults to 50, or 1  minimum dimension size of selected representation.
 zero_center :
bool
,None
If True, compute standard PCA from covariance matrix. If False, omit zerocentering variables (uses
TruncatedSVD
), which allows to handle sparse input efficiently. Passing None decides automatically based on sparseness of the data. svd_solver :
str
SVD solver to use:
 ’arpack’ (the default)
for the ARPACK wrapper in SciPy (
svds()
) ’randomized’
for the randomized algorithm due to Halko (2009).
 ’auto’
chooses automatically depending on the size of the problem.
 ’lobpcg’
An alternative SciPy solver.
Changed in version 1.4.5: Default value changed from ‘auto’ to ‘arpack’.
Efficient computation of the principal components of a sparse matrix currently only works with the ‘arpack’ or ‘lobpcg’ solvers.
 random_state :
None
,int
,RandomState
Change to use different initial states for the optimization.
 return_info :
bool
Only relevant when not passing an
AnnData
: see “Returns”. use_highly_variable :
bool
,None
Whether to use highly variable genes only, stored in .var[‘highly_variable’]. By default uses them if they have been determined beforehand.
 dtype :
str
Numpy data type string to which to convert the result.
 copy :
bool
If an
AnnData
is passed, determines whether a copy is returned. Is ignored otherwise. chunked :
bool
If True, perform an incremental PCA on segments of chunk_size. The incremental PCA automatically zero centers and ignores settings of random_seed and svd_solver. If False, perform a full PCA.
 chunk_size :
int
,None
Number of observations to include in each chunk. Required if chunked=True was passed.
Return type: AnnData
,ndarray
,spmatrix
Returns: X_pca (
spmatrix
,ndarray
) – If data is arraylike and return_info=False was passed, this function only returns X_pca…adata (anndata.AnnData) – …otherwise if copy=True it returns or else adds fields to adata:
 .obsm[‘X_pca’]
PCA representation of data.
 .varm[‘PCs’]
The principal components containing the loadings.
 .uns[‘pca’][‘variance_ratio’]
Ratio of explained variance.
 .uns[‘pca’][‘variance’]
Explained variance, equivalent to the eigenvalues of the covariance matrix.
 data :