scvelo.datasets.pancreas

scvelo.datasets.pancreas(file_path='data/Pancreas/endocrinogenesis_day15.h5ad')

Pancreatic endocrinogenesis

Data from Bastidas-Ponce et al. (2019).

Pancreatic epithelial and Ngn3-Venus fusion (NVF) cells during secondary transition with transcriptome profiles sampled from embryonic day 15.5.

Endocrine cells are derived from endocrine progenitors located in the pancreatic epithelium. Endocrine commitment terminates in four major fates: glucagon- producing α-cells, insulin-producing β-cells, somatostatin-producing δ-cells and ghrelin-producing ε-cells.

Parameters:

file_path : str, Path

Path where to save dataset and read it from.

Returns:

Returns adata object